The influence of plasticizers on the release of theophylline Morocco

The influence of plasticizers on the release of theophylline Morocco

The influence of plasticizers on the release of Theophylline

The aim of present work was to investigate the influence of plasticizer on the release of theophylline from microporous-controlled tablets. Three plasticizers, acetyltributyl citrate The influence of plasticizers on the release of theophylline The influence of plasticizers on the release of theophylline from microporous-controlled tablets. by W J Lin, H K Lee, D M Wang. Journal of controlled release : official journal of the Controlled Release Society. Read more related scholarly scientific articles and

Effect of different polymer-plasticizer combinations on ‘in

29/12/1995 · Plasticizers are added to the polymer coating of sustained-release granules to improve the mechanical properties of the coating shell. The present investigation evaluated the influence of different plasticizer/polymer combinations on theophylline (TH) release from Effect of different polymer-plasticizer combinations on in The release profiles of theophylline were influenced by the type and amount of plasticizer and of coating material, and by the ratio of polymer to plasticizer. A correlation was found between the permeability coefficients to water vapor of free films, having the same composition as those used for coating, and drug release.

The influence of plasticizers on the release of theophylline

Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): ntur.lib.ntu.edu.tw//ha… (external link) http Effect of different polymer-plasticizer combinations on ‘in 29/12/1995 · Abstract Plasticizers are added to the polymer coating of sustained-release granules to improve the mechanical properties of the coating shell. The present investigation evaluated the influence of different plasticizer/polymer combinations on theophylline (TH) release from pellets coated with latex aqueous dispersions of ethylcellulose (EC) or acrylic polymers (ACR). The plasticizers, present

Development of matrix-based theophylline sustained-release m

The influence of the compaction pressure, the plasticizer content used for the granulation of theophylline particles, and the amount of theophylline on the drug release were investigated. The effects of surface area and the addition of magnesium stearate as a hydrophobic agent on the drug release were studied. Influence of relative humidity on the mechanical and drug re The purpose of this study was to investigate the influence of relative humidity (RH) on the mechanical and dissolution properties of theophylline pellets coated with Eudragit((R)) RS 30 D/RL 30 D containing methylparaben (MP) as a non-traditional plasticizer. The

Effect of different polymer-plasticizer combinations on in

The release profiles of theophylline were influenced by the type and amount of plasticizer and of coating material, and by the ratio of polymer to plasticizer. A correlation was found between the permeability coefficients to water vapor of free films, having the same composition as those used for coating, and drug release. Development of matrix-based theophylline sustained-release m The influence of the compaction pressure, the plasticizer content used for the granulation of theophylline particles, and the amount of theophylline on the drug release were investigated. The effects of surface area and the addition of magnesium stearate as a hydrophobic agent on the drug release were studied.

Effect of cellulose acetate phthalate and polyethylene

ABSTRACT The present study describes the development of theophylline microcapsules by a non-solvent addition method and the effect of plasticizer addition on microencapsulation. The release was studied in distilled water and the data were analysed by various mathematical models for determining the mechanism of release. Effects of sphere size, polymer to drug ratio and plasticize Abstract Theophylline sustained release microspheres were prepared by applying the non-solvent addition method. The in-vitro release of the drug from the prepared microspheres of different size ranges (≤300, 300-600, 600-800, 800-1000 and 1000-1250 μm) was studied.

Development of matrix-based theophylline sustained-release m

1/1/2000 · Abstract. Microtablets containing high theophylline content (from 60% to 80%) based on a Eudragit RS PO matrix were produced on a rotary tablet press. The influence of the compaction pressure, the plasticizer content used for the granulation of theophylline particles, and the amount of theophylline on the drug release were investigated. Effect of cellulose acetate phthalate and polyethylene ABSTRACT The present study describes the development of theophylline microcapsules by a non-solvent addition method and the effect of plasticizer addition on microencapsulation. The release was studied in distilled water and the data were analysed by various mathematical models for determining the mechanism of release.

Effect of Plasticizer Systems with Eudragit® L-100 &

To investigate the effect of different plasticizer systems on the enteric protection of Theophylline multi-particulate beads coated with Eudragit® L-100 and Eudragit® S-100 polymers Influence of relative humidity on the mechanical and drug re The purpose of this study was to investigate the influence of relative humidity (RH) on the mechanical and dissolution properties of theophylline pellets coated with Eudragit((R)) RS 30 D/RL 30 D containing methylparaben (MP) as a non-traditional plasticizer. The

Effect of cellulose acetate phthalate and polyethylene

ABSTRACT The present study describes the development of theophylline microcapsules by a non-solvent addition method and the effect of plasticizer addition on microencapsulation. The release was studied in distilled water and the data were analysed by various mathematical models for determining the mechanism of release. matrix-formers via roller compaction: Influence of form Abstract The influence of plasticizer level, roll pressure and sintering temperature was investigated on the granule properties, tablet breaking force and theophylline release from tablets. Nine formulations using theophylline as a model drug, Eudragit ® RL PO, Eudragit ® RS PO, or both as a matrix former and triethyl citrate (TEC) as a plasticizer were prepared.

Plasticizers and their effects on microencapsulation process

27/9/2008 · The effect of different plasticizers, triethylcitrate, polyethylene glycol, propylene glycol, glycerin and citric acid, was investigated. Triethylcitrate, a water-insoluble plasticizer, produced a porous honeycomb-like microcapsule wall resulting in rapid drug release. Influence of an Acrylic Polymer Blend on the Physical Stabil 1/7/2009 · Influence of relative humidity on the mechanical and drug release properties of theophylline pellets coated with an acrylic polymer containing methylparaben as a non-traditional plasticizer. Eur J Pharm Biopharm. 2000;50(2):277–84.