Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat

Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat

Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat

4/1/2013 · Dibutyl phthalate (DBP; Figure 1) is one of the most popular phthalates used as clouding agent in beverages, which has been detected by the Taiwan Food and Drug Administration in 2011 []. Previous research has demonstrated that DBP is a developmental and reproductive toxicant that can reduce the binding of estrogen to estrogen receptors and inhibit estrogen’s transcriptional activity [ 3 ]. Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Dibutyl phthalate (DBP) is commonly used to increase the flexibility of plastics in industrial products. However, several plasticizers have been illegally used as clouding agents to increase dispersion of aqueous matrix in beverages. This study thus develops a rapid and validated analytical method by ultra-performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS) for the

Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat

CiteSeerX – Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Abstract: Dibutyl phthalate (DBP) is commonly used to increase the flexibility of plastics in industrial products. However, several plasticizers have been illegally used as clouding agents Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Deter Abstract Dibutyl phthalate (DBP) is commonly used to increase the &#;exibility of plastics in industrial products. However, several plasticizers have been illegally used as clouding agents to increase dispersion of aqueous matrix in beverages. Topics: dibutyl phthalate (DBP), liquid chromatography with tandem mass spectrometry (LC-MS/MS), pharmacokinetics, plasticizer, Chemistry, QD1

(PDF) Pharmacokinetics of dibutyl phthalate (DBP) in the rat

4/1/2013 · Dibutyl phthalate (DBP) is commonly used to increase the flexibility of plastics in industrial products. Chromatograms of ( A ) blank feces after protein precipatation ( B ) blank feces spike Pharmacokinetics of dibutylphthalate in pregnant rats. The objectives of this study were to evaluate the metabolism of DBP in female rats, and the pharmacokinetics of DBP in pregnant rats on gestational day (g.d.) 20. The identities of DBP metabolites in urine and in maternal and fetal plasma were confirmed by LC-MS/MS, as monobutylphthalate (MBP) and its glucuronide, monohydroxybutylphthalate and its glucuronide, and butanoic acid phthalate and

Pharmacokinetics of dibutylphthalate in pregnant rats | RTI

Dibutylphthalate (DBP) can cause adverse effects on the developing male reproductive tract when administered late in gestation to pregnant rats. The objectives of this study were to evaluate the metabolism of DBP in female rats, and the pharmacokinetics of DBP in pregnant rats on gestational day (g.d.) 20. The identities of DBP metabolites in urine and in maternal and fetal plasma were Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Deter Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): www.mdpi/1422-0067/… (external link)

Pharmacokinetics of dibutylphthalate in pregnant rats | RTI

Dibutylphthalate (DBP) can cause adverse effects on the developing male reproductive tract when administered late in gestation to pregnant rats. The objectives of this study were to evaluate the metabolism of DBP in female rats, and the pharmacokinetics of DBP in pregnant rats on gestational day (g.d.) 20. The identities of DBP metabolites in urine and in maternal and fetal plasma were Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Deter Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): www.mdpi/1422-0067/… (external link)

Dibutyl Phthalate (DBP)

Dibutyl phthalate (DBP) is listed as a category 1 endocrine disrupting chemical on the European Union’s list of potential endocrine disruptors. 2 DBP is considered a Substance of Very High Concern by the European Union due to reproductive toxicity and3 Dibutyl PhthalateDibutyl Phthalate 84-74-2 Hazard Summary Dibutyl phthalate is used in making flexible plastics that are found in a variety of consumer products. It appears to have relatively low acute (short-term) and chronic (long-term) toxicity. No information is available regarding

Pharmacokinetics of Dibutylphthalate in Pregnant Rats | Toxi

29/9/2004 · The objectives of this study were to evaluate the metabolism of DBP in female rats, and the pharmacokinetics of DBP in pregnant rats on gestational day (g.d.) 20. The identities of DBP metabolites in urine and in maternal and fetal plasma were confirmed by LC-MS/MS, as monobutylphthalate (MBP) and its glucuronide, monohydroxybutylphthalate and its glucuronide, and butanoic acid phthalate and Dibutyl PhthalateDibutyl Phthalate 84-74-2 Hazard Summary Dibutyl phthalate is used in making flexible plastics that are found in a variety of consumer products. It appears to have relatively low acute (short-term) and chronic (long-term) toxicity. No information is available regarding

Dibutyl Phthalate June 2008 – Industrial Chemicals

4 Overview This review of dibutyl phthalate (DBP) is a health hazard assessment only. For this assessment, two key reviews on DBP prepared by the European Chemicals Bureau and the US Centre for the Evaluation of Risks to Human Phthalate Di-butyl phthalate – GreenFactsPhthalate. Di-butyl phthalate. Context – Dibutyl Phthalate (DBP) is used in a wide range of products for everyday use such as plastics, paints, inks and cosmetics. Its widespread use has raised some concerns on the safety of this compound.

Pharmacokinetics of Dibutylphthalate in Pregnant Rats | Toxi

29/9/2004 · The objectives of this study were to evaluate the metabolism of DBP in female rats, and the pharmacokinetics of DBP in pregnant rats on gestational day (g.d.) 20. The identities of DBP metabolites in urine and in maternal and fetal plasma were confirmed by LC-MS/MS, as monobutylphthalate (MBP) and its glucuronide, monohydroxybutylphthalate and its glucuronide, and butanoic acid phthalate and solved: dibutyl phthalate (dbp) a plasticizer has a potentia Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Dibutyl phthalate (DBP; Figure 1) is one of the most popular phthalates used as clouding agent in beverages, which has been detected by the Taiwan Food and Drug Administration in 2011 .

Phthalate Di-butyl phthalate – GreenFacts

Phthalate. Di-butyl phthalate. Context – Dibutyl Phthalate (DBP) is used in a wide range of products for everyday use such as plastics, paints, inks and cosmetics. Its widespread use has raised some concerns on the safety of this compound. Dibutyl Phthalate (DBP)The Food Safety Commission of Japan (FSCJ) conducted a risk assessment of dibutyl phthalate (DBP) (CAS No.84–74-2) for the revision of the standards and criteria for apparatuses, containers and packages. The data used in the assessment include acute